SeqControl: Precision Guidance for Neural Control

Better targeting for brain stimulation treatments by better understanding sequences of neural activity.

About the Technology

Brain stimulation with minimally invasive electrodes could offer relief from psychiatric conditions ranging from depression to PTSD. But knowing exactly where to deliver the electrical stimulation is challenging, which leads to many patients remaining unresponsive to treatments. We need a way to move beyond “stim and pray.”

Our innovation uses computational tools to create a more nuanced picture of how activity flows within brain networks, allowing us to accurately stimulate a specific network in the brain involved in, for example, depression. By identifying both start and end sequences, as well as nodes in between, we can tailor minimally-invasive brain stimulation to the exact networks involved to treat a range of treatment-resistant psychiatric disorders. Additionally, our technology, already validated in preclinical studies, allows for bidirectional control, giving us the ability to both up- and downregulate activity.

Working with the HIT Fund, we hope to validate clinical need and refine our business model as we explore commercialization paths to bring our innovation to market.

Team Members