Notice to Researchers

Stanford has signed a license with Vical Incorporated to receive the right to practice patented technology which relates to the delivery of polynucleotides to vertebrates.  The license is for educational and internal research purposes only.   Under this license, Stanford has assumed the following obligations, with which you must comply if you use this technology:

• The technology (including any materials developed through its use – “Materials”) must be used only within Stanford and only by individuals (faculty, students, employees) who are obligated to assign inventions to Stanford.
• While you may provide the Materials to third parties, you should do so only after notifying the Office for Technology Licensing  (OTL) at 723-0651 so it can notify Vical of the transfer.
• If an invention or Material is created through the use of the technology, you should notify OTL (723-0651) so that OTL can notify Vical so that Vical can decide whether to exercise its option to negotiate a commercial license.

As of April 2, 2005, the following patent applications and issued patents are included in the license:

US Patent Applications

Expression of an exogenous polynucleotide sequence in a vertebrate

07/846,827

07/791,101

08/008,197

08/481,919

08/187,630

Issued US Patents

5,589,466  Induction of a protective immune response in a mammal by injecting a DNA sequence

5,703,055  Generation of antibodies through lipid mediated DNA delivery

5,580,859  Delivery of exogenous DNA sequences in a mammal

5,693,622  Expression of exogenous polynucleotide sequences cardiac muscle of a mammal

6,214,804  Induction of a protective immune response in a mammal by injecting a DNA sequence

6,228,844  Stimulating vascular growth by administration of DNA sequences encoding VEGF

6,413,942  Methods of delivering a physiologically active polypeptide to a mammal

6,673,776  Expression of exogenous polynucleotide sequences in a vertebrate, mammal, fish, bird human

6,706,694  Expression of exogenous polynucleotide sequences in a vertebrate

6,710,035  Generation of an immune response to a pathogen

6,867,195 Lipid-mediated polynucleotide administration to reduce likelihood of subject's becoming infected

If you have any questions, please call OTL at 723-0651 or kathy.ku@stanford.edu.